Cytolytic therapy
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Cytolytic therapy
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WebApr 11, 2024 · Oncolytic virotherapy is an emerging novel tumor therapeutic approach that selectively replicates in and destroys tumor cells while leaving normal cells undamaged. 1, 2 Initially, in the twentieth... WebApr 12, 2024 · ARZERRA (ofatumumab) is a CD20-directed cytolytic monoclonal antibody indicated for the treatment of chronic lymphocytic leukemia (CLL) in combination with chlorambucil, for the treatment of previously untreated patients with CLL for whom fludarabine-based therapy is considered inappropriate; in combination with fludarabine …
WebMay 18, 2006 · Peptide-based vaccines attempt to utilize antigenic epitopes derived from TAA for the induction of peptide-specific cytotoxic T lymphocytes (CTL) that can recognize and lyse tumor cells expressing these immunogenic peptides complexed with MHC Class I molecules on their cell surface. 1 One such example of a TAA is HER2/ neu, which is …
WebJul 1, 2014 · This remains an ongoing debate in the field—“purists” believe that it is the cytolytic activity of OVs that is the most important component of the platform whereas a … WebDefine cytolytic. cytolytic synonyms, cytolytic pronunciation, cytolytic translation, English dictionary definition of cytolytic. n. The dissolution or destruction of a cell. cy′to·lyt′ic adj. …
WebMar 31, 2024 · In vivo cell-derived xenograft models treated with PRAME mTCR CAR T cells demonstrated potent leukemia clearance and improved survival compared with unmodified T-cell controls. Furthermore, the cytolytic activity of PRAME mTCR CAR T cells was enhanced by treating the target cells with interferon gamma, which increases …
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