Web21 de fev. de 2024 · To monitor prolyl hydroxylase-dependent degradation of Hif-3α, we used reporter vector based on pEZX-FR02 cloning vector (GeneCopoeia) that contained HIF3A (NM_152794) gene region comprising ODD domain (oxygen-dependent degradation domain, amino acids 450-576) fused with firefly luciferase (without the ATG start codon) … WebHIF3A - hypoxia inducible factor 3 subunit alpha Gene. ... 关于 HIF3A. Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): This gene has 19 transcripts (splice variants), 191 orthologues and 7 paralogues. Broad expression in …
Tissue expression of HIF3A - Summary - The Human Protein Atlas
WebHif3a Gene Detail Summary Symbol. Hif3a Name. hypoxia inducible factor 3, alpha subunit. ... Gene Model ID Feature Type Coordinates Select Strains; C57BL/6J: … Web21 de mar. de 2024 · Complete information for EPAS1 gene (Protein Coding), Endothelial PAS Domain Protein 1, including: function, proteins, disorders, pathways, orthologs, and expression. ... Note=Colocalizes with HIF3A in the nucleus and speckles. {ECO:0000250 UniProtKB:P97481}. Q99814-EPAS1_HUMAN; tsg cursos
HIF1A Gene - GeneCards HIF1A Protein HIF1A Antibody
WebHIF3A Gene. HIF3A. The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many … Web15 de jul. de 2024 · Additionally, the roles of HIF3α, the third member of the HIFs, are still enigma due to its various splicing variants and the complicated phenotypes of Hif3a-gene modified mouse lines. Here, we summarize how molecular systems fine-tune hypoxia-inducible transcription with the cooperation of HIFs and their negative regulators, … Web27 de jun. de 2016 · The hypothesis that HIF pathways may play an important role in the development of AT dysfunction in obesity and genetic variants in HIF3A are related to parameters of AT distribution and function is tested. Recently, a genome-wide analysis identified DNA methylation of the HIF3A (hypoxia-inducible factor 3A) as strongest … tsg crawford