WebMar 9, 2012 · Tsc2 in mouse embryonic fibroblasts and knockdown of tsc1a in zebrafish cause increased ciliary length (9, 11, 38). The first animal models of TSC were generated by conven-tional inactivation of the Tsc1 or Tsc2 genes and revealed an absolute requirement of either gene during embryonic devel-opment, as homozygous mutants died before ...
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WebThese studies may evaluate genetic interactions between causative genes (Halbritter et al., 2013) or even extend the analysis to other genes involved in the generation of symptoms [i.e., tsc1a (DiBella et al., 2009); bbs4 and bbs8 (Hudak et al., 2010); or tekt1 (Ryan et al., 2024)]. Models for Skeletal Dysplasia Affecting Long Bones and/or ... WebFind the best pricing for Optifuse TSC-1A by comparing bulk discounts from 7 distributors. Octopart is the world's source for TSC-1A availability, pricing, and technical specs and other electronic parts. WebAug 29, 2024 · Zebrafish are increasingly being utilized as a model system to investigate the function of the growing list of risk genes associated with neurodevelopmental disorders. This is due in large part to the unique features of zebrafish that make them an optimal system for this purpose, including rapid, external development of transparent embryos, … notube convert youtube to mp4